Dietary Supplementation of Alpha Lipoic Acid on Serum Lipid Profile of Broiler Chicken Fed With Animal Fat Diet

The objective of this study was to determine the effects of alpha lipoic acid on the performance and serum lipid profile in broiler chicken. In this study, eighty, day-old Venn Cobb commercial broiler chicks broiler chicks were randomly distributed into two treatment groups with four replicates of ten birds each and the birds were fed with experimental diets T1 (Control ration as per BIS [1992] specifications with five per cent animal fat) and T2 (control ration supplemented with 100 mg of alpha lipoic acid/kg diet). The broiler starter ration (23 per cent crude protein and 2800 kcal ME/kg of feed) fed up to 4 weeks of age and finisher ration (20 per cent crude protein and 2900 kcal ME/kg of feed) fed up to 6 weeks of age. At the end of 42 days of experimental period, five birds from each treatment were slaughtered and blood was collected for serum biochemical analysis. The growth performance was similar in both the treatment groups. Similarly, serum cholesterol, triglycerides and VLDL-cholesterol level was not affected by the alpha lipoic acid supplemented group. However, serum HDLcholesterol level was significantly (P<0.01) increased in alpha lipoic acid supplemented group, whereas, LDL-cholesterol was reduced (P<0.01) in alpha lipoic acid supplemented group compared to control group. On conclusion, alpha lipoic acid supplementation had no effect on serum cholesterol, triglycerides and VLDL-cholesterol levels, but reduced the LDL-cholesterol level and increased the HDL-cholesterol level of broilers compared to control group.